VitalityIQ™ Sulforaphane with Sulfodyne® Broccoli Seed Extract & Sprout Powder

Sulforaphane has been difficult to deliver in an enriched and stable form for purposes of direct human consumption. Until now. Introducing:

VitalityIQ Sulforaphane with the key ingredient SULFODYNE®

Stabilised Sulforaphane Supplement with a patented extraction from broccoli seeds.

Harness antioxidant, anti-inflammatory and detox properties to support your body's natural defences, promote healthy aging and boost cellular health. And that's just the tip of the iceberg.

A lab verified (see test results) minimum of 22mg of sulforaphane per 2 capsule serving. Most Sulforaphane supplements contain no Sulforaphane at all. Only precursors.

• SUMMARY
• WHY SULFORAPHANE?
• CONTENTS

• VitalityIQ Sulforaphane contains a broccoli seed extract using a patented extraction technique that enables the creation of the world's first stabilised sulforaphane that can be made available as a supplement. Pioneered in France. From the creators of Prostaphane.
  
  Each bottle of VitalityIQ Sulforaphane contains 60 capsules, with 11mg of sulforaphane each.
  
  If you take a Sulforaphane supplement, you're either getting:
  
  A) Just glucoraphanin [Most common, cheapest, least bioavailable, labelled as sulforaphane glucosinolate]
  
  B) Combination of glucoraphanin and myrosinase [improved bioavailability]
  
  Or very rarely, you can find:
  
  C) Stabilised Sulforaphane, especially from broccoli seed extract [pricey, most bioavailable, effective, predictable dose].
  
  
  Why Choose VitalityIQ Stabilised Sulforaphane?
  
  Predictable Health Benefits: Clinical studies point to a daily sulforaphane intake of 20mg to 60mg for optimal health benefits. Our supplement delivers this targeted dose reliably, something difficult to achieve with diet alone due to varying glucoraphanin levels in broccoli and individual differences in gut microbiome effectiveness.
  
  Convenience and Efficiency: Consuming the equivalent sulforaphane amount from broccoli or sprouts is not only impractical due to the large required servings but also variable due to cooking methods (steaming for less than 3 minutes is the only viable way to preserve myrosinase and therefore, most of the conversion potential to sulforaphane) and biological differences. Our supplement simplifies your health regimen, providing a consistent and high sulforaphane yield without the bulk or variability of food sources.
  
  Bypassing Dietary Limitations: Cooking destroys the myrosinase enzyme necessary for converting glucoraphanin to sulforaphane, relying solely on gut bacteria for this conversion. Our stabilized supplement circumvents this issue, ensuring efficient sulforaphane delivery regardless of dietary habits or gut health.
  
  Assured Quality and Potency: The uncertainty of glucoraphanin content in broccoli seeds or sprouts poses a challenge for those seeking to leverage sulforaphane's benefits through diet. Our supplement offers a lab-verified, high-potency alternative, guaranteeing you receive the health-promoting compounds you need without the uncertainty.
  
  
  How does one choose the best Sulforaphane Supplement?
  Sulforaphane can activate a comprehensive network of protective pathways in the body. There are various forms of sulforaphane supplements available in the market, but choosing the right one does not have to be confusing. Here are some tips to help you make an informed choice:
  

  Aspect	VitalityIQ Sulforaphane SULFODYNE®	Glucoraphanin and Myrosinase	Sulforaphane Glucosinolate (a.k.a. glucoraphinin)	Raw Brocolli Sprout Power
  Sulforaphane Yield	Predictable dose; no need for myrosinase. Stabilised 5%	Variable 1% to 2%	Typically 0.1%	0.4% to 2.32%
  Bioavailability (How much of what you ingest is actually used?)	Predictable bioavailability 70%	In the presence of myrosinase: 35% to 40%	No myrosinase present 5% to 10%
  Supplementation Strategy	No additional myrosinase needed; Predictable dose	Needs myrosinase source for effectiveness.	Myrosinase source necessary for activation. Consume with myrosinase containing foods.	Daily Greens Powder
  Clinical Implications	Predictable dose. Preferred.	2nd choice	Limited effectiveness	n/a
  Cost per mg of sulforaphane	Lowest cost per mg of sulforaphane	Medium	High	unknown
  Stability	High; stable formulation ensures long shelf life. Encapsulation for extra protection.	Lower; myrosinase activity can decrease over time.	Stability depends on processing and storage conditions.	Fragile
  Brands	V.IQ	Avmacol	Broccoraphanin®, Crucera-SGS	BrocON
  Cost per day	$2.66			AU$4.33
  Type	Capsule	Tablet	Capsule	Powder

  Bioavailability data: https://chemoprotectioncenter.org/frequently-asked-questions/
  
  Cooking destroys Myrosinase
  Cruciferous vegetables, containing glucosinolates, are converted by myrosinases to isothiocyanates (ITC), promoting genes against oxidative stress. Cooking can inactivate myrosinases (anything over steaming for 3 minutes), but (healthy) gut flora can also create myrosinase and do some conversion. Another tip: Adding mustard seed powder while cooking broccoli may increase viable cooking temperature and time 90 degrees) as it seems to have a form of myrosinase much more heat resistant.
  
  Glucosinolate individual conversion rates vary widely (1-40%), but broccoil seed extracts show higher uniform conversion (70-90%). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618677/
  
  Sulforaphane Supplement Shopping Guide
  1. Look for supplements that contain actual sulforaphane. As a second best option, choose a combination of glucoraphanin and myrosinase. Avoid glucoraphinin (confusingly called Sulforaphane Glucosinolate).

  2. Choose supplements that use a standardized extract like Sulfodyne (5%) to ensure consistent and predictable dosage. Consider supplements that are formulated with broccoli seed or sprouts, as they are a natural source of sulforaphane and have been found to have higher bioavailability.

  3. Avoid supplements that contain fillers or additives, as they can affect the bioavailability and efficacy of the supplement.
  
  4. Choose a suppplement that transparently shows you a batch test result.
  
  5. Be aware of labelling confusion: Many products claim high sulforaphane content without clarifying bioavailability or standardisation. Some will use micrograms, μg, (1000x less) instead of milligrams (mg).

  6. Raw Broccoli Sprouts are the most concentrated food source of sulforaphane and can give you 10 times more sulforaphane than mature broccoli. We encourage eating them. Our supplement is advantageous because it is both convenient and offers a predictable dose.
  
  7. Broccoli Seed extracts have a higher sulforaphane yield than Sprout Powders.

  
  VitalityIQ Sulforaphane uses a stabilised & bioactive sulforaphane for enhanced absorption, bioavailability and potency.
  
  Useable Sulforaphane. Not just Precursors
• Unlike other similar supplements, we provide real sulforaphane and not just precursors. The problem with precursors is that they must first be converted into sulforaphane in the body. This can be highly inefficient due to a dependancy on enzymatic activity and also overall microbiome health.
  
  Made with SULFODYNE®, the same active ingredient in Prostaphane®, the top sulforaphane supplement recommended by Dr. Rhonda Patrick.
  
  Sulfodyne® is 70% bioavailable which is 2x more than other sulforaphane supplements.
  
  

  All sulforaphane is heat-sensitive. That's why we overpack each capsule with more than the stated 220mg. We also display our verifying lab test result. This helps mitigate loss over time. We also store our ingredients in a refrigerator.

  Why Choose Sulforaphane?
  Sulforaphane has higher bioavailability than other popular plant extract supplements known for their antioxidant and anti-inflammatory effect: curcumin, quercetin, silymarin, and resveratrol. (source)

  
  
  When comparing supplement options, stabilised sulforaphane offers the most bioavailability:
  

  
  

  
  

  VitalityIQ™ Sulforaphane offers better value, both in terms of:

  1. A concentrated dose of stabilised sulforaphane

  2. A lower cost per dose vs other supplements with lower absorption rates.

  
  What's the right dose of sulforaphane?
  Day to day maintenance requirements also differ from those of someone with a specific health concern. So it could be anything from 20mg to 60mg per day. Depending on your source:
  
  200mg SULFODYNE® =10mg per capsule (Stabilised sulforaphane. Predictable)

  
  200g Broccoli = 0.5mg to 18mg (Source and Preparation variable)
  
  200g Sprouts = 5mg - 60mg (Source & Preparation variability)
  
  Source: Dr Jed Fahey discusses his research with Dr Rhonda Patrick
  
  
  
  

• In comparison to commonly used supplements that contain phytochemicals, such as curcumin, silymarin, and resveratrol, sulforaphane is more effective in activating Nrf2, thereby stimulating the expression of a myriad of genes that offer essential cytoprotective properties.

  Further, due to its lipophilic properties and lower molecular weight, sulforaphane has a greater bioavailability than other dietary supplements that function on Nrf2 activation by polyphenols. Once Nrf2 is activated, it stimulates the expression of cytoprotective genes that are crucial in cellular defense mechanisms such as maintaining redox status and detoxification processes. (source)

  Cruciferous vegetables including broccoli sprouts, contain glucoraphin which has a depency on myrosinase to form sulforaphane. The constitution of the gut microbiome (that produce myrosinase) influences the quantity of sulforaphane produced. source

  
  

  The Health Benefits of Sulforaphane Include:

  Rank	Health Issue	Potential Benefit	Reference
  1	Cardiovascular health	Improved cardiovascular health by reducing blood pressure, cholesterol levels, and inflammation	Wu et al., 2004
  2	Obesity prevention	Suppression of obesity development by inhibiting adipogenesis and promoting lipolysis	Choi et al., 2014
  3	Diabetes management	Regulation of blood sugar levels and improved insulin sensitivity	Bahadoran et al., 2013
  4	Antioxidant properties	Activation of the Nrf2 pathway to produce antioxidant enzymes, reducing oxidative stress and preventing age-related diseases	Li et al., 2018
  5	Anti-inflammatory effects	Alleviation of chronic inflammatory diseases by modulating pro-inflammatory molecules	Heiss et al., 2001
  6	Cancer prevention	Chemopreventive properties through inhibition of cancer cell growth and induction of apoptosis	Fahey et al., 2016
  7	Respiratory health	Improved respiratory health by enhancing reactive oxygen species removal and reducing airway inflammation	Ritz et al., 2014
  8	Neuroprotection	Protection of neurons from oxidative stress and inflammation, reducing the risk of neurodegenerative diseases	Tarozzi et al., 2013
  9	Skin health	Protection of the skin from UV radiation-induced damage and photoaging	Sikdar et al., 2016
  10	Detoxification support	Enhanced detoxification processes by increasing the production of enzymes involved in the elimination of harmful substances	Zhang et al., 1992

• 60 capsules per bottle. (30 x 2 capsule servings). 22mg of sulforaphane per serving.

  Each capsule contains a minimum of 11mg of sulforaphane from Sulfodyne (stabilised sulforaphane standardised to 5%). Made in France. Packed in Australia.

  Equivalent sulforaphane of 836g (9 cups) of broccoli per 2 capsules.

  No fillers or flow agents here!

  This supplement is non-GMO, gluten-free, vegan, gelatin-frree and contains no preservatives.

  All capsules are Kosher Pareve and Halal certified, and made in a cGMP and FDA-approved facility.

  
  Ingredients (per capsule)

  1. 220mg Sulfodyne® (11mg Sulforaphane) with 70% bioavailability

  2. 340mg Broccoli sprout powder

  The Vegetarian Capsules contain no preservatives, gelatin, wheat, gluten or animal by-products. To ensure complete safety, all capsules are Kosher Pareve and Halal certified, and made in a cGMP and FDA-approved facility.

  Take 1-2 capsules per day after a meal (avoid taking on an empty stomach.

  Until recently, it was not possible to provide a stabilised sulforaphane supplement, so that's why all the supplements on the market contained the precursors glucoraphin and myrosinase. According to Dr Jeff Fahey, about 60mg of broccoli sprouts a day is enough to start to convey some of the protective effects he has demonstrated at his lab. Jeff Fahey is a leading phytochemical researcher with a focus on sulforaphane.

  What makes a quality supplement? It should be made in a GMP certified facility, use non-gmo ingredients (including the capsule) make no false claims, have 3rd party lab testing to verify the quantities stated on the label and to show no contaimination, not use obscure acronyms, or unpronounceable ingredients or attempt to create confusion by using large numbers. For example: mcg (micrograms) is sometimes used on product labels, but it is only 1/1000 of a mg. Some other supplements proudly claim to have low excipients. Quite a boast when the claim should be no excipients

  We always advocate a whole food approach to nutrition. So if you're game, have a go at sprouting your own broccoli seeds. the Sprouted Australia website has complete instructions and equipment available. According to Dr Jeff Fahey, about 60mg of broccoli sprouts a day is enough to start to convey some of the protective effects he has demonstrated at his lab.

  Be it the sheer volume needed or the inconvenience of growing or finding fresh broccoli sprouts, an encapsulated supplement offers a compelling alternative.

  
  

  Sulfodyne® is a registered trademark of Ingood by Olga

Do I need to keep this refrigerated?

A cool and dry place is all that is necessary, but refrigeration can prolong potency.

What's the difference to SanBroc®, BroccoPhane® and BroccoRaphanin®

SanBroc® Broccoli Seed Extract 13% Glucoraphanin Plus Myrosinase Claims 60% conversion rate from glucoraphinin > sulforaphane Produced by Sanberb Bioscience Group in China.

BroccoPhane® is a broccoli sprout powder Standardized to 4000ppm Sulforaphane. This is 4mg/1000mg. Produced by Bioriginal in Europe.

BroccoRaphanin® Basic or Plus provides either 5% or 11% concentration of glucoraphinin. No myrosinase is present. hey have since made Activated BroccoRaphanin® available which claims 1.25% to 2.3% Sulforaphane.

Sulfodyne® is a Broccoli Seed Extract standardised to 5% stabilised sulforaphane made using a patented extraction process in France. If a capsule contained 220mg of the powder, you would get 11mg of sulforaphane. And we overpack each capsule by 20% just to make sure we deliver what we promise.

In summary, the first three ingredients described above all provide the sulforaphane precursors glucoraphin and myrosinase which means highly variable conversion to sulforaphane. Sulfodyne® is the only ingredient that provides bioactive sulforaphane.

Why don't I just eat more broccoli sprouts to get sulforaphane benefits?

You probably should eat more cruciferous vegetables and there are many good reasons to eat broccoli sprouts. They're a great source of fibre. Broccoli provides 44mg-171mg/100g while Broccoli sprouts are 10 to 20 times higher. (1153mg/100g)

Cooking or blanching broccoli at less than 100°C can increase its effectiveness by releasing the myrosinase enzyme. However, if this enzyme is destroyed during processing (like blanching for frozen broccoli) or overheating, then the sulforaphane benefit is mostly lost. However, steaming between 1 and 3 minutes can increase sulforaphane yield. (https://pubmed.ncbi.nlm.nih.gov/22471240/)

Everyone has myrosinase producing bacteria in their gut. 200g of Broccoli yields Glucoraphinin: 4mg to 150mg, which in turns, yields: 0.5mg to 18mg of sulforaphane. A large range because all broccoli is different based on genetics, the way it is treated, stored and cooked. 200g of Broccoli Sprouts yields 5mg and 60mg of sulforaphane. Cooking destroys myrosinase. Also, there is person-to-person variation in gut myrosinase. So there's a lot of variation between broccoli and also the amount of myrosinase in both broccoli and broccoli sprouts.