The Power of Microdosing, Psychobiotics & Ketone Esters

In this post:

1. Microdosing LSD can increase your reflex time to lightning speed, improve your balance to the point of perfection, increase your concentration until you experience “tunnel vision”, and make you impervious to weakness or pain.
2. Psychobiotics treat the brain through the stomach.
3. A crumb of gluten can ruin your day (even if you're not celiac) all because of the critical enzyme DPP-IV.
4. Ketone Esters get you into ketosis (6mmol/L) within 30 minutes.

Performance-Enhancing Psychedelics: Can LSD Make You Better at Sport?

The goal of microdosing is to ensure the drug is consumed in doses that are not acutely felt. This sweet spot of psychedelic consumption is considered by many extreme sports athletes as performance-enhancing, at least anecdotally.

“According to the combined reports of 40 years of use by the extreme sports underground, LSD can increase your reflex time to lightning speed, improve your balance to the point of perfection, increase your concentration until you experience “tunnel vision”, and make you impervious to weakness or pain. “LSD’s effects in these regards are in fact legendary, universal, and without dispute.”
- James Oroc, Psychedelics & Extreme Sport (pdf)

The World Anti-Doping Agency (WADA) currently does not specifically prohibit the use of classical psychedelics such as LSD or psilocybin in sport.

The agency does, however, prohibit pharmacological substances “with no current approval by any governmental regulatory health authority for human therapeutic use”, which would cover psychedelic drugs.

Despite this, WADA does not assume these substances are performance-enhancing.

Source: New Atlas

Psychobiotics Treating the Brain Through the Stomach

We’re host to millions of microbes that live in harmony on our skin or inside our organs.

Our gut bugs, for example, eat up leftovers and pump out chemicals—metabolites—that can help break down toxic food compounds and synthesize critical vitamins that our bodies absorb.

The gut talks extensively to the brain through multiple microbiome phone lines.

Gut bugs can pump out chemicals directly into the blood for a straight shot at the brain. Or they can interact with “neuropod cells” that line the gut, tapping into a direct electrical highway called the vagus nerve to send information up to certain neural circuits in the brain, altering their function.

We're at the tip of the iceberg in discovering the therapeutic potential for many diseases.

Source: Singularity Hub

Psychobiotic probiotic formulas like CogniBiotics® have been designed with clinically proven ingredients to help produce awesome mood, feelings of happiness, improved memory and focus.

Ditch the Gluten?

Gluten inhibits the critical enzyme Dipeptidyl Peptidase IV (DPP-IV). This may be what's making you fat and may be the cause of brain fog, headache, fatigue, joint and muscle pain, leg or arm numbness, dermatitis (eczema or skin rash), depression, and anemia - even if you don't have celiac disease.

Ingestion of gluten in amounts as small as 25-50mg of gluten may elicit an adverse reaction (that’s the size of a crumb!).

Non-celiac gluten sensitivity or even leaky gut, causes a combination of irritable bowel syndrome-like symptoms, including:

• abdominal pain
• bloating
• bowel habit abnormalities (either diarrhea or constipation)
• systemic manifestations such as 'foggy mind', headache, fatigue, joint and muscle pain, leg or arm numbness, dermatitis (eczema or skin rash), depression, and anemia.

A gluten free diet has shown symptomatic relief in non-celiac Irritable Bowl Disease patients. 65.6% of patients from a group of 1647 reported an improvement.

A DPP-IV enzyme containing supplement like Gluten Guardian can come in very handy for anyone with non-celiac-gluten-sensitivity or has leaky gut.

It works by breaking down the gluten protein into components that can be escorted out of the body before it has a chance to cause trouble in the small intestine. It should be noted that it won't be effective for a wheat allergy, since the individual may be reacting to a different component of the wheat.

Source: https://pubmed.ncbi.nlm.nih.gov/26605537/

Ketone Esters Are a (Not So) New Method to Generate Rapid and Significant Ketosis

Ingestion of Ketones Esters (KE) rapidly induces ketosis (above 6 mmol/L) in humans. KE is hydrolyzed into β-hydroxybutyrate (βHB) and its precursor 1,3-butanediol.

This study found that βHB uptake into the brain strongly correlated with the plasma βHB concentration and was preferentially distributed in the neocortex.

Oral KE led to an increase of acetyl-CoA and citric cycle intermediates in the brain of non-fasted mice.

Furthermore, increased level of acetyl-CoA inhibited glycolysis by a feedback mechanism and thus competed with glucose under physiological conditions.